Maurizio Giri's Max for Live effects both rely on granular synthesis to produce results ranging from subtle to overwhelming. The latest, Grain Reverser, reverses audio input and applies granular effects like transposition and duration variation, in addition to filtering.
Looking for some new and different synth sounds? Ableton's Simpler works great for playing bag a single waveform cyclically, like a wavetable synthesizer. Isaac Cotec aka Subaqueous has created a free Instrument Rack featuring custom waveforms and audio effects to complete a unique wavetable synth for Simpler - watch it in action below: